ATG4B anticorps

N° du produit ABIN2460952

Cet anticorps Lapin Polyclonal détecte spécifiquement ATG4B dans WB et ELISA. Il présente une réactivité envers Humain, Souris, Rat et Chien.

Aperçu rapide pour ATG4B anticorps (ABIN2460952)

Antigène: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG4B est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ATG4B anticorps

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ATG4B.

Information d'application

Indications d'application: ATG4B antibody can be used for detection of ATG4B by ELISA at 1:12500. ATG4B antibody can be used for detection of ATG4B by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ATG4B antibody at -20 °C.

Détails sur ATG4B

Antigène: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Autre désignation: ATG4B

Sujet: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. APG4B encodes a member of the autophagin protein family and is also designated as a member of the C-54 family of cysteine proteases.Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Poids moléculaire: 44 kDa, 36 kDa, 55 kDa, 54 kDa

ID gène: 23192

NCBI Accession: NP_037457

UniProt: Q9Y4P1

Pathways: Autophagy